Why is clonidine sedating
When considering combinations of drugs, knowledge of their context sensitive half-times is essential.
Propofol is extensively used in the intensive care setting as a sedative.
Background Sedation is an important treatment for critically ill patients who need a machine to support breathing, because it reduces anxiety and stress and facilitates the delivery of nursing care.
Sedation allows the depression of patients' awareness of the environment and reduction of their response to external stimulation.Concerns with clinical scoring systems include interpreter variability and a lack of clear discrimination between deeper levels of sedation.Ensuring patient comfort requires a multidisciplinary approach in addition to pharmacotherapy.How much sedation is given, and for how long, is important in determining patient outcome as both over and under-sedation can have potentially deleterious consequences.Over-sedation can increase time on ventilatory support and prolong ICU duration of stay.